High-quality RNA extraction from solid tissues remains one of the most failure-prone steps in molecular biology workflows. While downstream library preparation, qPCR, and sequencing chemistries have become increasingly robust, the integrity and yield of RNA remain fundamentally dependent on effective, reproducible tissue homogenization. Inadequate mechanical disruption results in incomplete lysis, low yields, and—most critically—RNA degradation due to prolonged exposure to endogenous RNases. For laboratories processing heterogeneous or fibrous tissues at scale, the Bullet Blender 50 Gold+ offers a controlled, high-throughput approach to tissue homogenization that prioritizes RNA integrity while minimizing operator-dependent variability. The Central Challenge: RNase Activity and Incomplete Lysis…
Author: John Norwood
John Norwood is best known as a technology journalist, currently at Ziddu where he focuses on tech startups, companies, and products.
Accurate cell counting and viability assessment remain foundational to nearly every cell-based workflow, yet they are also a persistent source of variability. As experimental systems become more complex—ranging from primary cells and co-cultures to engineered cell therapies—the limitations of manual counting and low-resolution automated systems become increasingly apparent. The LUNA-FX7 automated cell counter was developed to address these challenges by combining high-resolution imaging with flexible fluorescence-based analysis, positioning it as a quantitative platform rather than a simple counting device. Limitations of Conventional Cell Counting Approaches Manual hemocytometer counting remains widely used, despite well-documented issues with operator bias, low throughput, and poor…
Search engine optimization has evolved far beyond keyword stuffing and backlink volume. Modern SEO requires precision, data intelligence, and tools that adapt to constantly changing algorithms. Search Atlas has emerged as a comprehensive SEO platform designed to meet these demands, giving marketers, agencies, and business owners the ability to scale organic growth strategically rather than tactically. This article explores what Search Atlas is, how it works, and why it has become an essential tool for data-driven SEO success. What Is Search Atlas? Search Atlas is an all-in-one SEO software platform developed by LinkGraph. It combines keyword research, content optimization, technical…
In the world of credit and finance, few tools are as important and influential, as the Cash Reserve Ratio (CRR). Understanding the CRR and how its decisions affect the economy helps individuals and firms make sense of changing credit conditions and liquidity in India. CRR determines the flow of money by establishing the proportion of the cash or liquid money that lenders or institutions must set aside rather than put to work in the economy. Understanding CRR and its purpose in the banking system The CRR full form is Cash Reserve Ratio. As per a financial mandate of the Reserve Bank…
Initially developed by E. Jerome McCarthy and published in his book Basic Marketing: A Managerial Approach (1960), the “4 Ps of Marketing” has become an essential framework for developing effective marketing strategies that drive sustainable revenue growth. The 4 Ps stand for product, placement, price, and promotion. Many business owners and marketing professionals focus primarily on promotion, leaving product, placement, and pricing strategy siloed in other parts of the business and outside their overall marketing strategy. Those focusing on all 4 Ps of Marketing are in a stronger position to achieve their revenue and other growth goals faster and more…
Industrial and commercial cleaning projects vary widely in complexity, environment, and goals. Selecting the right surface-cleaning method depends on a range of factors—surface material, contaminant type, equipment sensitivity, and regulatory constraints, among others. In many cases, a combination of techniques may offer the most efficient, compliant, and cost-effective outcome. Understanding Dry Ice & Abrasive Blasting Dry ice blasting uses compressed air to propel frozen carbon dioxide (CO₂) pellets at a surface. On impact, the pellets sublimate—transforming directly from solid to gas—leaving no secondary waste. This makes it especially useful in environments where water, chemicals, or dust are not permissible, such…
High blood pressure, or hypertension, is one of the most common chronic conditions affecting older adults. While it can remain silent for years, its long-term effects on the heart, kidneys, brain, and blood vessels are significant. This is why understanding GERIATRICS Hypertension Wellness and Prevention is critical for maintaining vitality, independence, and a high quality of life in older age. In older adults, hypertension is more than just elevated numbers on a blood pressure monitor. Age-related changes in blood vessels, hormonal regulation, and organ function increase vulnerability, making proactive wellness and preventive strategies essential. For a complete overview, explore GERIATRICS…
Hypertension, commonly known as high blood pressure, is a widespread health concern among older adults. For individuals over 65, elevated blood pressure is not just a number—it’s a critical indicator of cardiovascular health and overall wellness. Understanding GERIATRICS Hypertension Wellness and Prevention is essential for maintaining a high quality of life, reducing the risk of heart disease, and supporting healthy aging. Hypertension in geriatric patients often develops gradually and may remain undetected for years. Fortunately, with proper awareness, lifestyle adjustments, and medical guidance, it is possible to prevent complications and maintain stable blood pressure throughout later life. Why Hypertension Prevention…
Hypertension, or high blood pressure, is often called the “silent killer,” and for good reason. Many older adults live with elevated blood pressure for years without realizing it, placing them at risk for heart attacks, strokes, kidney problems, and cognitive decline. That’s why understanding GERIATRICS Hypertension Diagnosis and Evaluation is essential for anyone involved in elder care—whether you’re a patient, caregiver, or healthcare professional. In geriatric patients, diagnosing hypertension isn’t as straightforward as checking a single blood pressure reading. Age-related changes in arteries, kidney function, and cardiovascular health mean clinicians must take a more detailed and individualized approach. For a…